If you decide to make bunches of blocks, assemble all of the pinwheels you need first, and then decide how many frame units to place between them. Placing complete blocks side-by-side will give you a double layer of frames where blocks meet. That's a good look, but if you prefer single frames some of your pinwheels can remain as-is.
You'll find an example of a quilt with single frames on page 3 -- a baby quilt pattern that's made with 6-inch framed Pinwheel blocks.
Jump over to page 4 to see how the Framed Pinwheel quilt block was used in in a Quilting Forum event a few years ago. Do take a look at the page, even if you don't plan to enter, because the color choices are fantastic.
Cutting Chart - One 12-inch Finished BlockDark Rose: two 4-7/8" x 4-7/8" squares
Light Rose: two 4-7/8" x 4-7/8" squares
Blue: four 2-1/2" x 8-1/2" bars
Pale Yellow: Four 2-1/2" x 2-1/2" squares
Cutting Chart - One 6-inch Finished BlockDark Rose: two 2-7/8" x 2-7/8" squares
Light Rose: two 2-7/8" x 2-7/8" squares
Blue: four 1-1/2" x 4-1/2" bars
Pale Yellow: Four 1-1/2" x 1-1/2" squares